Study of factors causing excess protoporphyrin accumulation in cultured skin fibroblasts from patients with protoporphyria.
The activity of heme synthetase, which catalyzes the chelation of ferrous iron to protoporphyrin to form heme, is deficient in sonicates of skin fibroblasts cultured from patients with protoporphyria. During culture in Eagle's medium supplemented with fetal calf serum, these cells do not accumulate...
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| 出版年: | J Clin Invest |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
1977
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372492/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/915001/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108895 |
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