Characterization of Deficient Heme Synthase Activity in Protoporphyria with Cultured Skin Fibroblasts
Heme synthase (ferrochelatase) activity, as determined by the chelation of ferrous iron to protoporphyrin or deuteroporphyrin, is reduced to 10-25% of normal in tissues of patients with protoporphyria. With cultured skin fibroblasts from seven patients with protoporphyria and six normal individuals,...
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| Publicado no: | J Clin Invest |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1980
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371370/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7356682/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109675 |
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