A functional interaction of Ku with Werner exonuclease facilitates digestion of damaged DNA

Werner syndrome (WS) is a premature aging disorder where the affected individuals appear much older than their chronological age. The single gene that is defective in WS encodes a protein (WRN) that has ATPase, helicase and 3′→5′ exonuclease activities. Our laboratory has recently uncovered a physic...

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Detalles Bibliográficos

Publicado en:	Nucleic Acids Res
Principais autores:	Orren, David K., Machwe, Amrita, Karmakar, Parimal, Piotrowski, Jason, Cooper, Marcus P., Bohr, Vilhelm A.
Formato:	Artigo
Idioma:	Inglês
Publicado:	Oxford University Press 2001
Assuntos:	Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC37248/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11328876/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.9.1926
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