The LDL Receptor-Related Protein 1 (LRP1) Regulates the PDGF Signaling Pathway by Binding the Protein Phosphatase SHP-2 and Modulating SHP-2- Mediated PDGF Signaling Events

BACKGROUND: The PDGF signaling pathway plays a major role in several biological systems, including vascular remodeling that occurs following percutaneous transluminal coronary angioplasty. Recent studies have shown that the LDL receptor-related protein 1 (LRP1) is a physiological regulator of the PD...

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Detalhes bibliográficos
Main Authors: Craig, Julie, Mikhailenko, Irina, Noyes, Nathaniel, Migliorini, Mary, Strickland, Dudley K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724782/
https://ncbi.nlm.nih.gov/pubmed/23922991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070432
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