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An Out-of-frame Overlapping Reading Frame in the Ataxin-1 Coding Sequence Encodes a Novel Ataxin-1 Interacting Protein

Spinocerebellar ataxia type 1 is an autosomal dominant cerebellar ataxia associated with the expansion of a polyglutamine tract within the ataxin-1 (ATXN1) protein. Recent studies suggest that understanding the normal function of ATXN1 in cellular processes is essential to decipher the pathogenesis...

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Hlavní autoři: Bergeron, Danny, Lapointe, Catherine, Bissonnette, Cyntia, Tremblay, Guillaume, Motard, Julie, Roucou, Xavier
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724639/
https://ncbi.nlm.nih.gov/pubmed/23760502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.472654
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