Direct Detection of Alternative Open Reading Frames Translation Products in Human Significantly Expands the Proteome

A fully mature mRNA is usually associated to a reference open reading frame encoding a single protein. Yet, mature mRNAs contain unconventional alternative open reading frames (AltORFs) located in untranslated regions (UTRs) or overlapping the reference ORFs (RefORFs) in non-canonical +2 and +3 read...

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Autors principals: Vanderperre, Benoît, Lucier, Jean-François, Bissonnette, Cyntia, Motard, Julie, Tremblay, Guillaume, Vanderperre, Solène, Wisztorski, Maxence, Salzet, Michel, Boisvert, François-Michel, Roucou, Xavier
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741303/
https://ncbi.nlm.nih.gov/pubmed/23950983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070698
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