Spatially-Resolved Top-down Proteomics Bridged to MALDI MS Imaging Reveals the Molecular Physiome of Brain Regions

Tissue spatially-resolved proteomics was performed on 3 brain regions, leading to the characterization of 123 reference proteins. Moreover, 8 alternative proteins from alternative open reading frames (AltORF) were identified. Some proteins display specific post-translational modification profiles or...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Mol Cell Proteomics
Autori principali: Delcourt, Vivian, Franck, Julien, Quanico, Jusal, Gimeno, Jean-Pascal, Wisztorski, Maxence, Raffo-Romero, Antonella, Kobeissy, Firas, Roucou, Xavier, Salzet, Michel, Fournier, Isabelle
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2018
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5795397/
https://ncbi.nlm.nih.gov/pubmed/29122912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M116.065755
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