Combined Mass Spectrometry Imaging and Top-down Microproteomics Reveals Evidence of a Hidden Proteome in Ovarian Cancer

BACKGROUND: Recently, it was demonstrated that proteins can be translated from alternative open reading frames (altORFs), increasing the size of the actual proteome. Top-down mass spectrometry-based proteomics allows the identification of intact proteins containing post-translational modifications (...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Principais autores: Delcourt, Vivian, Franck, Julien, Leblanc, Eric, Narducci, Fabrice, Robin, Yves-Marie, Gimeno, Jean-Pascal, Quanico, Jusal, Wisztorski, Maxence, Kobeissy, Firas, Jacques, Jean-François, Roucou, Xavier, Salzet, Michel, Fournier, Isabelle
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514399/
https://ncbi.nlm.nih.gov/pubmed/28629911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.06.001
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