α-Synuclein Oligomers Impair Neuronal Microtubule-Kinesin Interplay

Early α-synuclein (α-Syn)-induced alterations are neurite pathologies resulting in Lewy neurites. α-Syn oligomers are a toxic species in synucleinopathies and are suspected to cause neuritic pathology. To investigate how α-Syn oligomers may be linked to aberrant neurite pathology, we modeled differe...

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Bibliographische Detailangaben
Hauptverfasser: Prots, Iryna, Veber, Vanesa, Brey, Stefanie, Campioni, Silvia, Buder, Katrin, Riek, Roland, Böhm, Konrad J., Winner, Beate
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Neurobiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724632/
https://ncbi.nlm.nih.gov/pubmed/23744071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.451815
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