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Cigarette Smoke Component Acrolein Modulates Chromatin Assembly by Inhibiting Histone Acetylation

Chromatin structure and gene expression are both regulated by nucleosome assembly. How environmental factors influence histone nuclear import and the nucleosome assembly pathway, leading to changes in chromatin organization and transcription, remains unknown. Acrolein (Acr) is an α,β-unsaturated ald...

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Main Authors: Chen, Danqi, Fang, Lei, Li, Hongjie, Tang, Moon-shong, Jin, Chunyuan
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724627/
https://ncbi.nlm.nih.gov/pubmed/23770671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.476630
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