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Mechanisms Underlying Acrolein-Mediated Inhibition of Chromatin Assembly

Acrolein is a major component of cigarette smoke and cooking fumes. Previously, we reported that acrolein compromises chromatin assembly; however, underlying mechanisms have not been defined. Here, we report that acrolein reacts with lysine residues, including lysines 5 and 12, sites important for c...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Cell Biol
Päätekijät: Fang, Lei, Chen, Danqi, Yu, Clinton, Li, Hongjie, Brocato, Jason, Huang, Lan, Jin, Chunyuan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108886/
https://ncbi.nlm.nih.gov/pubmed/27669733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00448-16
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