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Cigarette Smoke Component Acrolein Modulates Chromatin Assembly by Inhibiting Histone Acetylation

Chromatin structure and gene expression are both regulated by nucleosome assembly. How environmental factors influence histone nuclear import and the nucleosome assembly pathway, leading to changes in chromatin organization and transcription, remains unknown. Acrolein (Acr) is an α,β-unsaturated ald...

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Detalhes bibliográficos
Main Authors: Chen, Danqi, Fang, Lei, Li, Hongjie, Tang, Moon-shong, Jin, Chunyuan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724627/
https://ncbi.nlm.nih.gov/pubmed/23770671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.476630
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