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Substrate Binding Stabilizes a Pre-translocation Intermediate in the ATP-binding Cassette Transport Protein MsbA

ATP-binding cassette (ABC) transporters belong to one of the largest protein superfamilies that expands from prokaryotes to man. Recent x-ray crystal structures of bacterial and mammalian ABC exporters suggest a common alternating access mechanism of substrate transport, which has also been biochemi...

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Sonraí Bibleagrafaíochta
Main Authors: Doshi, Rupak, van Veen, Hendrik W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724623/
https://ncbi.nlm.nih.gov/pubmed/23766512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.485714
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