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Molecular Disruption of the Power Stroke in the ATP-binding Cassette Transport Protein MsbA

ATP-binding cassette transporters affect drug pharmacokinetics and are associated with inherited human diseases and impaired chemotherapeutic treatment of cancers and microbial infections. Current alternating access models for ATP-binding cassette exporter activity suggest that ATP binding at the tw...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Doshi, Rupak, Ali, Anam, Shi, Wilma, Freeman, Elizabeth V., Fagg, Lisa A., van Veen, Hendrik W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591591/
https://ncbi.nlm.nih.gov/pubmed/23306205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.430074
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