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Molecular Disruption of the Power Stroke in the ATP-binding Cassette Transport Protein MsbA
ATP-binding cassette transporters affect drug pharmacokinetics and are associated with inherited human diseases and impaired chemotherapeutic treatment of cancers and microbial infections. Current alternating access models for ATP-binding cassette exporter activity suggest that ATP binding at the tw...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3591591/ https://ncbi.nlm.nih.gov/pubmed/23306205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.430074 |
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