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Increased cAMP in Monocytes Augments Notch Signaling Mechanisms by Elevating RBP-J and Transducin-like Enhancer of Split (TLE)

In cells of the innate immune system, pathological increases in intracellular cAMP attenuate immune responses and contribute to infections by bacteria such as Bacillus anthracis. In this work, cAMP from B. anthracis edema toxin (ET) is found to activate the Notch signaling pathway in both mouse macr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Larabee, Jason L., Shakir, Salika M., Barua, Soumitra, Ballard, Jimmy D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724613/
https://ncbi.nlm.nih.gov/pubmed/23775085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.465120
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