TGFβ1 Inhibition Increases the Radiosensitivity of Breast Cancer Cells In Vitro and Promotes Tumor Control by Radiation In Vivo

PURPOSE: To determine whether inhibition of TGFβ signaling prior to irradiation sensitizes human and murine cancer cells in vitro and in vivo. EXPERIMENTAL DESIGN: TGFβ-mediated growth and Smad phosphorylation of MCF7, Hs578T, MDA-MB-231, and T47D human breast cancer cell lines were examined and cor...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Bouquet, Fanny, Pal, Anupama, Pilones, Karsten A., Demaria, Sandra, Hann, Byron, Akhurst, Rosemary J., Babb, Jim S., Lonning, Scott M., DeWyngaert, J. Keith, Formenti, Silvia C., Barcellos-Hoff, Mary Helen
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724539/
https://ncbi.nlm.nih.gov/pubmed/22028490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-0544
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados