Oxidized low-density lipoproteins induce rapid platelet activation and shape change through tyrosine kinase and Rho kinase–signaling pathways

Oxidized low-density lipoproteins (oxLDL) generated in the hyperlipidemic state may contribute to unregulated platelet activation during thrombosis. Although the ability of oxLDL to activate platelets is established, the underlying signaling mechanisms remain obscure. We show that oxLDL stimulate pl...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Wraith, Katie S., Magwenzi, Simbarashe, Aburima, Ahmed, Wen, Yichuan, Leake, David, Naseem, Khalid M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2013
Assuntos:
Platelets and Thrombopoiesis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724193/
https://ncbi.nlm.nih.gov/pubmed/23699602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-04-491688
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares