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Oxidized low-density lipoproteins induce rapid platelet activation and shape change through tyrosine kinase and Rho kinase–signaling pathways

Oxidized low-density lipoproteins (oxLDL) generated in the hyperlipidemic state may contribute to unregulated platelet activation during thrombosis. Although the ability of oxLDL to activate platelets is established, the underlying signaling mechanisms remain obscure. We show that oxLDL stimulate pl...

詳細記述

保存先:
書誌詳細
主要な著者: Wraith, Katie S., Magwenzi, Simbarashe, Aburima, Ahmed, Wen, Yichuan, Leake, David, Naseem, Khalid M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724193/
https://ncbi.nlm.nih.gov/pubmed/23699602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-04-491688
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