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MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability

Fat is stored or mobilized according to food availability. Malfunction of the mechanisms that ensure this coordination underlie metabolic diseases in humans. In mammals, lysosomal and autophagic function is required for normal fat storage and mobilization in the presence or absence of food. Autophag...

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Detalhes bibliográficos
Main Authors: O’Rourke, Eyleen J., Ruvkun, Gary
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723461/
https://ncbi.nlm.nih.gov/pubmed/23604316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2741
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