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Fat Metabolism Links Germline Stem Cells and Longevity in C. elegans

Fat metabolism, reproduction, and aging are intertwined regulatory axes; however, the mechanism by which they are coupled remains poorly understood. We found that germline stem cells (GSCs) actively modulate lipid hydrolysis in Caenorhabditis elegans, which in turn regulates longevity. GSC arrest pr...

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Main Authors: Wang, Meng C., O’Rourke, Eyleen J., Ruvkun, Gary
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760269/
https://ncbi.nlm.nih.gov/pubmed/18988854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1162011
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