A conserved human T cell population targets mycobacterial antigens presented by CD1b

T cell receptors (TCRs) pair in millions of combinations to create complex and personally unique T cell repertoires. Using tetramers to analyze CD1b-reactive TCRs, we detected T cells with highly stereotyped TCR α chains present among genetically unrelated tuberculosis patients. These germline-encod...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Van Rhijn, Ildiko, Kasmar, Anne, de Jong, Annemieke, Gras, Stephanie, Bhati, Mugdha, Doorenspleet, Marieke E., de Vries, Niek, Godfrey, Dale I., Altman, John, de Jager, Wilco, Rossjohn, Jamie, Moody, D. Branch
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723453/
https://ncbi.nlm.nih.gov/pubmed/23727893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2630
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