A conserved human T cell population targets mycobacterial antigens presented by CD1b

T cell receptors (TCRs) pair in millions of combinations to create complex and personally unique T cell repertoires. Using tetramers to analyze CD1b-reactive TCRs, we detected T cells with highly stereotyped TCR α chains present among genetically unrelated tuberculosis patients. These germline-encod...

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Detalhes bibliográficos
Main Authors: Van Rhijn, Ildiko, Kasmar, Anne, de Jong, Annemieke, Gras, Stephanie, Bhati, Mugdha, Doorenspleet, Marieke E., de Vries, Niek, Godfrey, Dale I., Altman, John, de Jager, Wilco, Rossjohn, Jamie, Moody, D. Branch
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723453/
https://ncbi.nlm.nih.gov/pubmed/23727893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2630
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