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T cell receptor bias and affinity define two compartments of the CD1b-glycolipid specific T cell repertoire

Current views emphasize T cell receptor (TCR) diversity as a key feature that differentiates the group 1 (CD1a, CD1b, CD1c) and group 2 (CD1d) CD1 systems. Whereas TCR sequence motifs define CD1d-reactive NKT cells, the available data do not allow a TCR-based organization of the group 1 CD1 repertoi...

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Detalhes bibliográficos
Main Authors: Van Rhijn, Ildiko, Gherardin, Nicholas A., Kasmar, Anne, de Jager, Wilco, Pellicci, Daniel G., Kostenko, Lyudmila, Tan, Li Lynn, Bhati, Mugdha, Gras, Stephanie, Godfrey, Dale I., Rossjohn, Jamie, Moody, D. Branch
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019959/
https://ncbi.nlm.nih.gov/pubmed/24683194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400158
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