Hypoxia enhances innate immune activation to Aspergillus fumigates through cell wall modulation

Infection by the human fungal pathogen Aspergillus fumigatus induces hypoxic microenvironments within the lung that can alter the course of fungal pathogenesis. How hypoxic microenvironments shape the composition and immune activating potential of the fungal cell wall remains undefined. Herein we de...

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Main Authors: Shepardson, Kelly M., Ngo, Lisa Y., Aimanianda, Vishukumar, Latge, Jean-Paul, Barker, Bridget M., Blosser, Sara J., Iwakura, Yoichiro, Hohl, Tobias M., Cramer, Robert A.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723392/
https://ncbi.nlm.nih.gov/pubmed/23220005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2012.11.010
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