Myeloid Derived Hypoxia Inducible Factor 1-alpha Is Required for Protection against Pulmonary Aspergillus fumigatus Infection

Hypoxia inducible factor 1α (HIF1α) is the mammalian transcriptional factor that controls metabolism, survival, and innate immunity in response to inflammation and low oxygen. Previous work established that generation of hypoxic microenvironments occurs within the lung during infection with the huma...

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Main Authors: Shepardson, Kelly M., Jhingran, Anupam, Caffrey, Alayna, Obar, Joshua J., Suratt, Benjamin T., Berwin, Brent L., Hohl, Tobias M., Cramer, Robert A.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2014
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177996/
https://ncbi.nlm.nih.gov/pubmed/25255025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004378
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