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Aspergillus fumigatus Trehalose-Regulatory Subunit Homolog Moonlights To Mediate Cell Wall Homeostasis through Modulation of Chitin Synthase Activity

Trehalose biosynthesis is found in fungi but not humans. Proteins involved in trehalose biosynthesis are essential for fungal pathogen virulence in humans and plants through multiple mechanisms. Loss of canonical trehalose biosynthesis genes in the human pathogen Aspergillus fumigatus significantly...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Thammahong, Arsa, Caffrey-Card, Alayna K., Dhingra, Sourabh, Obar, Joshua J., Cramer, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405227/
https://ncbi.nlm.nih.gov/pubmed/28442603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00056-17
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