Aspergillus fumigatus Trehalose-Regulatory Subunit Homolog Moonlights To Mediate Cell Wall Homeostasis through Modulation of Chitin Synthase Activity

Trehalose biosynthesis is found in fungi but not humans. Proteins involved in trehalose biosynthesis are essential for fungal pathogen virulence in humans and plants through multiple mechanisms. Loss of canonical trehalose biosynthesis genes in the human pathogen Aspergillus fumigatus significantly...

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Veröffentlicht in:mBio
Hauptverfasser: Thammahong, Arsa, Caffrey-Card, Alayna K., Dhingra, Sourabh, Obar, Joshua J., Cramer, Robert A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405227/
https://ncbi.nlm.nih.gov/pubmed/28442603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00056-17
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