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Endoplasmic reticulum localized PerA is required for cell wall integrity, azole drug resistance, and virulence in Aspergillus fumigatus

GPI-anchoring is a universal and critical post-translational protein modification in eukaryotes. In fungi, many cell wall proteins are GPI-anchored, and disruption of GPI-anchored proteins impairs cell wall integrity. After being synthesized and attached to target proteins, GPI anchors undergo modif...

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Detalhes bibliográficos
Main Authors: Chung, Dawoon, Thammahong, Arsa, Shepardson, Kelly M., Blosser, Sara J., Cramer, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112376/
https://ncbi.nlm.nih.gov/pubmed/24779420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12626
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