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Development of Azole Resistance in Aspergillus fumigatus during Azole Therapy Associated with Change in Virulence
Four sequential Aspergillus fumigatus isolates from a patient with chronic granulomatous disease (CGD) eventually failing azole-echinocandin combination therapy were investigated. The first two isolates (1 and 2) were susceptible to antifungal azoles, but increased itraconazole, voriconazole and pos...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2852403/ https://ncbi.nlm.nih.gov/pubmed/20404915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010080 |
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