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Emerging roles of DMP1 in lung cancer

The Ras-activated transcription factor DMP1 can stimulate Arf transcription to promote p53-dependent cell arrest. One recent study deepens the pathophysiological significance of this pathway in cancer, first, by identifying DMP1 losses in human lung cancers that lack ARF/p53 mutations, and second, b...

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Detalhes bibliográficos
Main Authors: Inoue, Kazushi, Sugiyama, Takayuki, Taneja, Pankaj, Morgan, Rachel L., Frazier, Donna P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723119/
https://ncbi.nlm.nih.gov/pubmed/18559489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6791
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