Defective Axonal Transport of Rab7 GTPase Results in Dysregulated Trophic Signaling

Retrograde trophic signaling of nerve growth factor (NGF) supports neuronal survival and differentiation. Dysregulated trophic signaling could lead to various neurological disorders. Charcot-Marie-Tooth type 2B (CMT2B) is one of the most common inherited peripheral neuropathies characterized by seve...

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Detalhes bibliográficos
Main Authors: Zhang, Kai, Fishel Ben Kenan, Rotem, Osakada, Yasuko, Xu, Wei, Sinit, Rachel S., Chen, Liang, Zhao, Xiaobei, Chen, Jia-Yun, Cui, Bianxiao, Wu, Chengbiao
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722856/
https://ncbi.nlm.nih.gov/pubmed/23616551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4322-12.2013
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