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Visualizing Directional Rab7 and TrkA Cotrafficking in Axons by pTIRF Microscopy
Rab7 GTPase is known to regulate protein degradation and intracellular signaling via endocytic sorting and is also known to be involved in peripheral neurodegeneration. Mutations in the GTP-binding pocket of Rab7 cause Charcot–Marie–Tooth type 2B (CMT-2B) neuropathy. It has been suggested that the C...
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| Publicado no: | Methods Mol Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5061505/ https://ncbi.nlm.nih.gov/pubmed/25800854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-2569-8_27 |
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