The C-type lectin receptor CLEC4M binds, internalizes, and clears von Willebrand factor and contributes to the variation in plasma von Willebrand factor levels

Genetic variation in or near the C-type lectin domain family 4 member M (CLEC4M) has been associated with plasma levels of von Willebrand factor (VWF) in healthy individuals. CLEC4M is a lectin receptor with a polymorphic extracellular neck region possessing a variable number of tandem repeats (VNTR...

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Detalhes bibliográficos
Main Authors: Rydz, Natalia, Swystun, Laura L., Notley, Colleen, Paterson, Andrew D., Riches, J. Jacob, Sponagle, Kate, Boonyawat, Boonchai, Montgomery, Robert R., James, Paula D., Lillicrap, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722568/
https://ncbi.nlm.nih.gov/pubmed/23529928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-10-457507
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