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Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration

Age-related macular degeneration (AMD) is a complex, degenerative and progressive eye disease that usually does not lead to complete blindness, but can result in severe loss of central vision. Risk factors for AMD include age, genetics, diet, smoking, oxidative stress and many cardiovascular-associa...

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Bibliografiske detaljer
Main Authors: Kaarniranta, Kai, Sinha, Debasish, Blasiak, Janusz, Kauppinen, Anu, Veréb, Zoltán, Salminen, Antero, Boulton, Michael E., Petrovski, Goran
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722332/
https://ncbi.nlm.nih.gov/pubmed/23590900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.24546
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