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Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration

Age-related macular degeneration (AMD) is a complex, degenerative and progressive eye disease that usually does not lead to complete blindness, but can result in severe loss of central vision. Risk factors for AMD include age, genetics, diet, smoking, oxidative stress and many cardiovascular-associa...

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Autors principals: Kaarniranta, Kai, Sinha, Debasish, Blasiak, Janusz, Kauppinen, Anu, Veréb, Zoltán, Salminen, Antero, Boulton, Michael E., Petrovski, Goran
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722332/
https://ncbi.nlm.nih.gov/pubmed/23590900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.24546
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