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Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration

Age-related macular degeneration (AMD) is a complex, degenerative and progressive eye disease that usually does not lead to complete blindness, but can result in severe loss of central vision. Risk factors for AMD include age, genetics, diet, smoking, oxidative stress and many cardiovascular-associa...

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Détails bibliographiques
Auteurs principaux: Kaarniranta, Kai, Sinha, Debasish, Blasiak, Janusz, Kauppinen, Anu, Veréb, Zoltán, Salminen, Antero, Boulton, Michael E., Petrovski, Goran
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722332/
https://ncbi.nlm.nih.gov/pubmed/23590900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.24546
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