Mechanisms of mitochondrial dysfunction and their impact on age-related macular degeneration

Oxidative stress-induced damage to the retinal pigment epithelium (RPE) is considered to be a key factor in age-related macular degeneration (AMD) pathology. RPE cells are constantly exposed to oxidative stress that may lead to the accumulation of damaged cellular proteins, lipids, nucleic acids, an...

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Bibliographic Details
Published in:Prog Retin Eye Res
Main Authors: Kaarniranta, Kai, Uusitalo, Hannu, Blasiak, Janusz, Felszeghy, Szabolcs, Kannan, Ram, Kauppinen, Anu, Salminen, Antero, Sinha, Debasish, Ferrington, Deborah
Format: Artigo
Language:Inglês
Published: 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650008/
https://ncbi.nlm.nih.gov/pubmed/32298788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.preteyeres.2020.100858
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