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Discovery of bisulfite-mediated cytosine conversion to uracil, the key reaction for DNA methylation analysis — A personal account

Methylation at position 5 of cytosine in DNA is being intensively studied in many areas of biological sciences, as the methylation is intimately associated with the control of gene functions. The principal analytical method for determining the sites of 5-methylcytosine in genome at the sequence leve...

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Autor principal: Hayatsu, Hikoya
Format: Artigo
Idioma:Inglês
Publicat: The Japan Academy 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722019/
https://ncbi.nlm.nih.gov/pubmed/18941305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2183/pjab/84.321
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