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Discovery of bisulfite-mediated cytosine conversion to uracil, the key reaction for DNA methylation analysis — A personal account

Methylation at position 5 of cytosine in DNA is being intensively studied in many areas of biological sciences, as the methylation is intimately associated with the control of gene functions. The principal analytical method for determining the sites of 5-methylcytosine in genome at the sequence leve...

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Bibliographic Details
Main Author: Hayatsu, Hikoya
Format: Artigo
Language:Inglês
Published: The Japan Academy 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722019/
https://ncbi.nlm.nih.gov/pubmed/18941305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2183/pjab/84.321
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