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Deletion of the A gamma-globin gene in G gamma-delta beta-thalassemia.

In an individual homozygous for G gamma-delta beta-thalassemia, a physical alteration in gamma-globin gene organization was detected by restriction enzyme mapping. The data indicated that the absence of A gamma-globin chains resulted from extension of the DNA deletion from the delta beta-globin gene...

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Udgivet i:J Clin Invest
Principais autores: Orkin, S H, Alter, B P, Altay, C
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1979
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372193/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/468997/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109535
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