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Gamma delta beta-thalassaemias 1 and 2 are the result of a 100 kbp deletion in the human beta-globin cluster.

The DNA spanning two large deletions in the human beta-globin gene cluster (gamma beta-thalassaemia 1 and 2) has been cloned by cosmid cloning and chromosomal walking. The entire region was mapped and analyzed for the presence of repetitive sequences. The results show that the affected loci have los...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Taramelli, R, Kioussis, D, Vanin, E, Bartram, K, Groffen, J, Hurst, J, Grosveld, F G
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1986
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC311714/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3763397/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/14.17.7017
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