Biphasic effects of prostaglandin E2 on the human fat cell adenylate cyclase.

Adenylate cyclase of human fat cell ghosts shows a biphasic response towards prostaglandin E2 with inhibition occurring at nanomolar concentrations of the hormone and stimulation at concentrations beyond 10(-6) mol/liter. The expression of the inhibitory effect is critically dependent on GTP. Under...

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Pubblicato in:	J Clin Invest
Autori principali:	Kather, H, Simon, B
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1979
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372157/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/457871/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109500
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