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Biphasic effects of prostaglandin E2 on the human fat cell adenylate cyclase.

Adenylate cyclase of human fat cell ghosts shows a biphasic response towards prostaglandin E2 with inhibition occurring at nanomolar concentrations of the hormone and stimulation at concentrations beyond 10(-6) mol/liter. The expression of the inhibitory effect is critically dependent on GTP. Under...

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Bibliographic Details
Main Authors: Kather, H, Simon, B
Format: Artigo
Language:Inglês
Published: 1979
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC372157/
https://ncbi.nlm.nih.gov/pubmed/457871
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