Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF

Several pathological processes, such as sepsis and inflammatory bowel disease (IBD), are associated with impairment of intestinal epithelial barrier. Here, we investigated the role of matrix metalloproteinase MMP13 in these diseases. We observed that MMP13(−/−) mice display a strong protection in LP...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Vandenbroucke, Roosmarijn E, Dejonckheere, Eline, Van Hauwermeiren, Filip, Lodens, Sofie, De Rycke, Riet, Van Wonterghem, Elien, Staes, An, Gevaert, Kris, López-Otin, Carlos, Libert, Claude
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Blackwell Publishing Ltd 2013
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721470/
https://ncbi.nlm.nih.gov/pubmed/23723167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201202100
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