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Development of multi-epitope vaccines targeting wild-type (wt) sequence p53 peptides

Loss of p53 tumor suppressor function is the most common abnormality in human cancer, which can result in enhanced presentation to immune cells of wild type sequence (wt) peptides from tumor p53 molecules, provides the rationale for wt p53 peptide-based cancer vaccines. We review evidence from precl...

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Main Authors: DeLeo, Albert B., Whiteside, Theresa L.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721363/
https://ncbi.nlm.nih.gov/pubmed/18767952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14760584.7.7.1031
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