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CD8+ T cell recognition of polymorphic wild-type sequence p53(65–73) peptides in squamous cell carcinoma of the head and neck

The TP53 tumor suppressor gene contains a well-studied polymorphism that encodes either proline (P) or arginine (R) at codon 72, and over half of the world’s population is homozygous for R at this codon. The wild-type sequence (wt) p53 peptide, p53(65–73), has been identified as a CD8+ T cell-define...

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Main Authors: Andrade Filho, Pedro A., Ito, Daisuke, DeLeo, Albert B., Ferris, Robert L.
格式: Artigo
語言:Inglês
出版: Springer-Verlag 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109029/
https://ncbi.nlm.nih.gov/pubmed/20577877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-010-0886-1
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