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IRX-2, a novel immunotherapeutic, protects human T cells from tumor-induced cell death

IRX-2 is a cytokine-based biologic agent that has the potential to enhance antitumor immune responses. We investigated whether IRX-2 can protect T cells from tumor-induced apoptosis. Tumor-derived microvesicles (MV) expressing FasL were purified from supernatants of tumor cells and incubated with ac...

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Main Authors: Czystowska, M, Han, J, Szczepanski, MJ, Szajnik, M, Quadrini, K, Brandwein, H, Hadden, JW, Signorelli, K, Whiteside, TL
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721331/
https://ncbi.nlm.nih.gov/pubmed/19180118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2008.197
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