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A diametric role for OX40 in the response of effector/memory CD4(+) T cells and regulatory T cells to alloantigen

OX40 is a member of the TNFR superfamily that has potent costimulatory properties. Although the impact of blockade of the OX40-OX40L pathway has been well documented in models of autoimmune disease, its effect on the rejection of allografts is less well defined. Here we show that the alloantigen-med...

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Hlavní autoři: Kinnear, Gillian, Wood, Kathryn J., Fallah-Arani, Farnaz, Jones, Nick D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721124/
https://ncbi.nlm.nih.gov/pubmed/23817421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300553
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