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Potential Capacity of Aptamers to Trigger Immune Activation in Human Blood

Target specific short single-stranded DNA (ssDNA) molecules, called aptamers, are auspicious ligands for numerous in vivo applications. However, aptamers are synthetic molecules, which might be recognized by the immune cells in vivo and induce an activation of the innate immune system. Thus, immune...

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書誌詳細
主要な著者: Avci-Adali, Meltem, Steinle, Heidrun, Michel, Tatjana, Schlensak, Christian, Wendel, Hans P.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720859/
https://ncbi.nlm.nih.gov/pubmed/23935890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068810
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