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Potential Capacity of Aptamers to Trigger Immune Activation in Human Blood

Target specific short single-stranded DNA (ssDNA) molecules, called aptamers, are auspicious ligands for numerous in vivo applications. However, aptamers are synthetic molecules, which might be recognized by the immune cells in vivo and induce an activation of the innate immune system. Thus, immune...

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Detalhes bibliográficos
Main Authors: Avci-Adali, Meltem, Steinle, Heidrun, Michel, Tatjana, Schlensak, Christian, Wendel, Hans P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720859/
https://ncbi.nlm.nih.gov/pubmed/23935890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068810
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