Bioactive lipids sphingosine-1-phosphate and ceramide-1-phosphate are pro-metastatic factors in human rhabdomyosarcomas cell lines, and their tissue level increases in response to radio/chemotherapy

We observed that sphingosine-1-phosphate (S1P) and ceramide-1-phosphate (C1P) strongly enhance in vitro motility and adhesion of human rhabdomyosarcoma (RMS) cells. This effect was observed at physiological concentrations of both bioactive lipids, which are present in biological fluids, and is much...

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Detalhes bibliográficos
Main Authors: Schneider, Gabriela, Bryndza, Ewa, Abdel-Latif, Ahmed, Ratajczak, Janina, Maj, Magdalena, Tarnowski, Maciej, Klyachkin, Yurij, Houghton, Peter, Morris, Andrew J., Vater, Axel, Klussmann, Sven, Kucia, Magdalena, Ratajczak, Mariusz Z.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720846/
https://ncbi.nlm.nih.gov/pubmed/23615526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-12-0600
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