Evidence for the involvement of sphingosine-1-phosphate in the homing and engraftment of hematopoietic stem cells to bone marrow

The α-chemokine stromal-derived factor 1 (SDF-1), which binds to the CXCR4 receptor, directs migration and homing of CXCR4(+) hematopoietic stem/progenitor cells (HSPCs) to bone marrow (BM) stem cell niches. Nevertheless, it is also known that CXCR4(−/−) fetal liver-derived hematopoietic stem cells...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Adamiak, Mateusz, Borkowska, Sylwia, Wysoczynski, Marcin, Suszynska, Malwina, Kucia, Magda, Rokosh, Gregg, Abdel-Latif, Ahmed, Ratajczak, Janina, Ratajczak, Mariusz Z.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2015
Onderwerpen:
Research Paper: Pathology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662458/
https://ncbi.nlm.nih.gov/pubmed/26299919
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