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BAFF- and APRIL-dependent maintenance of Ab titers after immunization with T-dependent Ag and CD1d-binding ligand

CD1d-restricted invariant Natural Killer T (iNKT) cells boost humoral immunity to T-dependent Ags that are co-administered with the CD1d-binding glycolipid Ag α-galactosylceramide (α-GC). Observations that mice lacking iNKT cells have decaying Ab responses following vaccination has led to the hypoth...

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Autori principali: Shah, Hemangi B., Joshi, Sunil K., Rampuria, Pragya, Devera, T. Scott, Lang, Gillian A., Stohl, William, Lang, Mark L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720783/
https://ncbi.nlm.nih.gov/pubmed/23797666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300263
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